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Imaging MS Sample Preparation

The principle of MALDI MS is based on the introduction of a UV-activated matrix molecule in the immediate proximity of the analyte, so it is imperative to control the process by which matrix is introduced in the sample.  Unique in design, the HTX TM-Sprayer Instruments provides heat to the nebukised matrix solution to accelerate adsorption into the tissue, as well as a controlled flow of dry air or nitrogen to focus the spray and control drying time. HTX Sprayers, are a unique solution to the matrix deposition challenge.

The new HTX M5 Sprayer has a whole range of new features, expanding your sample prep capability and offering improved performance. The M5 has full software control of the system, including the pump and optional heated tray.

The TM-Sprayer™ Tissue MALDI Sample Preparation System is designed to provide the highest quality matrix deposition on the two-dimensional biological samples, and can be integrated with any MALDI Mass Spectrometer platform.

Poster download:

Metabolite Profiling in Tissues from whole body slices via improved Liquid Microjunction Surface Sampling by LC-HRMS