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fixed flow splitter
-
performance note
-
information
- The ASI Fixed Flow Splitter divides inlet flow into two, three
or four channels
- Factory preset split ratios from 1:1 to 20,000:1
- Fluid resistor technology replaces long capillary tubing to
create split ratio
- Simple low cost design that does not require any calibration or
adjustment
- Small size allows closer placement to the detector
- Ultra low dead volume fluidic design for minimal
dispersion
- Input flow rate from 0.1 mL/min. up to 1 L/min. (Higher flow
rate are available by request)
- Stable and reproducible split flows are not affected by
viscosity or pressure changes in post-column applications
- Maximum 350 bar operating pressure
- Available in binary, three and four port configurations
The ratio of the fluid resistor
values determines the split ratio. This ratio is calibrated
within a +/- 10% tolerance range, assuming that there is no
pressure drop down stream from the splitter. Input flow rate
may be adjusted to compensate for variation within tolerance.
For example, a 10% increase in input flow rate will yield a
10% flow increase at both high and low flow channels. The
pressure drop specification for all input flow ranges is 500 PSI
maximum with water at the calibration flow rate. When
ordering, please specify the actual inlet flow rate if it is
significantly different from the default calibration flow rate.
Typical uses for post-column flow splitting
Multiple
detectors:
Split between 2 or more detectors
such as mass spec and evaporative light scattering, UV, or IR.
This is especially important when one of the detectors is
destructive, such as Mass Spectroscopy and ELS.
LC/MS:
Reduce the flow rate from the
column to a lower flow rate that the mass spec can work efficiently
at. Chromatography methods are often using flow rates of 0.5 to 2
mL/min., which are too high for most mass spec. Flow
splitting is a way to reduce the flow rate down to flow rates
suitable for the mass spec.
Although there are pumps that
can deliver flow rates low enough to be compatible with mass spec,
many practical reasons prevent Chromatographers from changing
methods that are already proven to work at higher flow rates:
reluctance to change to a different column from one that is
familiar and accepted; FDA regulations and S.O.P's that make any
changes in methods burdensome; the ease of operation at higher
mL/min. flow rates compared to µL/min. flow rates. Flow
splitting allows the chromatographer to take a proven method that
works at higher flow rates and quickly integrate mass spec or
multiple detectors without re-developing the method.